Open Protocols

Protocol Name	Investigatory Role	Biomarkers	Data Collections
Biomarker Dev Lab At Moffitt Supplement	Leading	0	0
The Biomarker Knowledge System Informatics Pilot Project Supplement To The Biomarker Development Laboratory at Moffitt (Bedlam)	Coordinating	0	0
The Early Detection Research Network: Biomarker Reference Laboratories	Involved	0	0

Closed Protocols

Protocol Name	Investigatory Role	Biomarkers	Data Collections
EDRN Resource Network Exchange	Involved	0	0
Protocol for Comparing Promoter Hypermethylation Methods in NSCLC	Coordinating	0	0
Standard Specimen Reference Set: Lung	Involved	0	0

Publications

Publication Name	PubMed ID	Journal
A systematic review and lessons learned from early lung cancer detection trials using low-dose computed tomography of the chest.	12915809	Cancer Control
Advances in sputum analysis for screening and early detection of lung cancer.	10740657	Cancer Control
Consensus statements from the Second International Lung Cancer Molecular Biomarkers Workshop: a European strategy for developing lung cancer molecular diagnostics in high risk populations.	12118333	Int J Oncol
Considerations in developing successful, population-based molecular screening and prevention of lung cancer.	11147628	Cancer
Data mining techniques for cancer detection using serum proteomic profiling.	15364092	Artif Intell Med
Defective transforming growth factor beta signaling pathway in head and neck squamous cell carcinoma as evidenced by the lack of expression of activated Smad2.	11410498	Clin Cancer Res
Diagnosis of roentgenographically occult lung cancer by sputum cytology.	11901920	Clin Chest Med
Differential expression of FEZ1/LZTS1 gene in lung cancers and their cell cultures.	12114433	Clin Cancer Res
Discovery of distinct protein profiles specific for lung tumors and pre-malignant lung lesions by SELDI mass spectrometry.	12781425	Lung Cancer
Evaluating serial observations of precancerous lesions for further study as a trigger for early intervention.	12210622	Stat Med
Expression of early lung cancer detection marker: hnRNP-A2/B1 and its relation to microsatellite alteration in non-small cell lung cancer.	11714531	Lung Cancer
Genetic analysis of microsomal epoxide hydrolase gene and its association with lung cancer risk.	15901990	Eur J Cancer Prev
Loss of heterogeneous ribonucleoprotein A(2)/B(1) expression in thyroid neoplasms.	11421561	Endocr Pract
Lung cancer evolution to preinvasive management.	11901918	Clin Chest Med
Lung cancer: chemoprevention and intermediate effect markers.	11220665	IARC Sci Publ
Microsatellite instability at AAAG repeat sequences in respiratory tract cancers.	11146445	Int J Cancer
Moving to the routine management of pre symptomatic lung cancer.	11720735	Lung Cancer
Polymorphisms for microsomal epoxide hydrolase and genetic susceptibility to COPD.	15702235	Int J Mol Med
Polymorphisms of the DNA repair gene XRCC1 and lung cancer risk.	11219768	Cancer Epidemiol Biomarkers Prev
Screening for lung cancer with CT: a preliminary cost-effectiveness analysis.	12006436	Chest
The early detection of occult lung cancer.	11091923	Chest Surg Clin N Am
The human 8-oxoguanine DNA N-glycosylase 1 (hOGG1) DNA repair enzyme and its association with lung cancer risk.	15077011	Pharmacogenetics
Transforming growth factor-beta type II receptors and smad proteins in follicular thyroid tumors.	10942134	Laryngoscope

Interests

Lung Cancer Early Detection

The goal of my Molecular Screening Program is to conduct translational research into the discovery of markers of neoplastic transformation and the use of these markers to screen for cancer risk and early detection in specimens from human populations.

To update protocols, publications, biomarkers, or science data, please contact the Data Management and Coordinating Center.

Site

H. Lee Moffitt Cancer Center

Degree(s)

M.D., Ph.D.

Email

Melvyn.Tockman@moffitt.org

Fax

(813) 745-1720

Person ID

1017

EDRN Title

EDRN Associate Member

Note

To update contact information, please visit the Data Management and Coordinating Center .