HEDS Ref Set App: UTSW: Singal (2024)

Abbreviated Name
HEDS Ref Set App: Singal (2024)
Lead Investigator
No lead investigator
Coordinating Investigator
No coordinating investigator
Involved Investigators

Abstract

No abstract availalbe.

Aims

1.   Characterize semi-annual surveillance and proportion time covered by surveillance in patients with cirrhosis 2.   Identify factors associated with proportion time covered by surveillance 3.   Evaluate the association between proportion time covered by surveillance and early-stage HCC detection

Analytic Method

We will characterize imaging receipt as semi-annual (at least one imaging study every 6 months during the study period), annual (imaging at least once per year but not sufficient to meet the semi-annual threshold), sporadic (at least one imaging study during the study period but not meeting threshold for annual) or none. We will also calculate proportion time covered (PTC) by surveillance. Imaging studies (ultrasound, 4-phase CT, or MRI) are considered to provide 3 months of surveillance coverage if a suspicious liver lesion ≥1 cm was detected and 6 months of coverage if no lesion or a lesion under <1cm are detected. Single-phase CT or non-contrast CT/MRI exams are not included when calculating PTC given lack of robust data supporting their role for HCC surveillance. PTC is calculated by dividing the number of covered months (based on surveillance tests and corresponding results) by the number of months in the study.

Publications

  • No publications available at this time for this protocol.

Biomarkers

  • No biomarkers available at this time for this protocol.

Data Collections

  • No data collections available at this time for this protocol.
Start Date
Aug 1 2024
Protocol ID
588
Protocol Type
Collaboration
Fields of Research
  • Other
Collaborative Group
G.I. and Other Associated Cancers Research Group
Cancer Types
  • Liver cell carcinoma

Associated Forms